Serotonergic modulation of acetylcholine release in the rat dorsal hippocampus.

نویسندگان
چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Effect of isolation rearing on pre- and post-synaptic serotonergic function in the rat dorsal hippocampus.

Several behavioural, neurochemical, and structural alterations found in isolation-reared rats are similar to those in human schizophrenia. This study investigated changes in cholinergic and serotonergic function in the hippocampus following isolation rearing. Rats were reared in social isolation from weaning for 6 weeks before study and compared to group-reared rats. An in vitro electrophysiolo...

متن کامل

Kappa Opioid Modulation of Serotonergic Neurotransmission in the Hypothalamus, Hippocampus and Striatum in the Male Rat

Objectives: We have investigated the modulatory effects of κ-opioid receptors on the central serotonergic system in the hypothalamus, hippocampus and striatum. Materials and Methods: Male Sprague-Dawley rats (n=32) used in the experiments were divided into four groups. Anaesthetized animals were mounted on a stereotaxic apparatus and intracerebroventricularly infused with U-50488H (κ-agonist, 5...

متن کامل

Coexistence of muscarinic acetylcholine receptors and somatostatin in nonpyramidal neurons of the rat dorsal hippocampus.

This study describes the colocalization of muscarinic acetylcholine receptors (mAChRs) and the neuropeptide somatostatin (SOM) in nonpyramidal neurons of the rat dorsal hippocampus. SOM and mAChRs were identified by immunocytochemistry employing antibody S309 and M35, respectively. Half of the SOMergic cell population is found to be immunoreactive for muscarinic receptor protein as obtained by ...

متن کامل

Modification of adenosine modulation of acetylcholine release in the hippocampus of aged rats.

Adenosine is a neuromodulator acting through inhibitory A(1) receptors (A(1)Rs) and facilitatory A(2A)Rs. Since A(2A)R antagonists attenuate memory deficits in aged animals and memory deficits might involve a decreased cholinergic function, we investigated how aging affects the density and function of adenosine receptors in rat hippocampal cholinergic terminals. In young adult (2 months) rats, ...

متن کامل

Choline enhances scopolamine-induced acetylcholine release in dorsal hippocampus of conscious, freely-moving rats.

We examined the effects of exogenous choline (30, 60, 120 mg/kg, i.p.) on basal and scopolamine-evoked acetylcholine (ACh) release in awake animals, using in vivo microdialysis. After collection of 3-4 baseline dialysate samples (15 min each), rats received either saline or choline chloride and 4 additional samples were collected. All animals then received scopolamine hydrochloride (0.5 mg/kg, ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Japanese Journal of Pharmacology

سال: 1993

ISSN: 0021-5198

DOI: 10.1016/s0021-5198(19)51358-0